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. 2018 Jan 31;2018:6051407. doi: 10.1155/2018/6051407

Figure 3.

Figure 3

MiR-29b downregulates the expression of Mcl-1 and CCND2. (a and b) The potential binding sites of miR-29b on the 3′ UTR of Mcl-1 and CCND2. (c) The expression of Mcl-1 and CCND2 in PASMCs treated with the miR-29b mimic, inhibitor, or control by Western blot. (d and e) The effect of the miR-29b mimic and inhibitor on the wildtype and mutant 3′ UTR of Mcl-1 as analyzed by a luciferase assay. (f and g) The effect of the miR-29b mimic and inhibitor on the wildtype and mutant 3′ UTR of CCND2 as analyzed by a luciferase assay. ∗p < 0.05 and ∗∗p < 0.01.