Table 2.
List of miRNAs potentially involved in a feedback loop to modulate the calcineurin/NFAT signaling pathway. Eleven miRNAs are identified in this study to be involved in a feedback loop with target genes and expression in human activated T cells.
| miRNAs Involved in Feedback Loops | Target Genes | miRNA Average Expression in Activated T Cells (RPM) |
|---|---|---|
| hsa-miR-21-3p | CALM1 | 191 |
| hsa-let-7b-5p | NFATC1 | 8617 |
| hsa-miR-17-5p | PPP3R1 | 778 |
| hsa-miR-17-3p | STIM1 | 859 |
| hsa-miR-19a-3p | ITPR1 | 4379 |
| hsa-miR-92b-3p | ITPR1 | 254 |
| hsa-miR-21-5p | CSNK1A1 | 372,670 |
| hsa-miR-181c-5p | CSNK1A1 | 321 |
| hsa-let-7c-5p | GSK3A | 889 |
| hsa-let-7b-3p | GSK3B | 77 |
| hsa-miR-155-5p | GSK3B | 282,932 |