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. 2016 Oct 25;2(4):12. doi: 10.3390/ncrna2040012

Figure 1.

Figure 1

Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) interacts with the C-terminal dsRBD of human Dicer. The interaction between TWEAK and truncated forms of human Dicer was tested in a yeast two-hybrid system using strain PJ69-4A. The activity of the adenine (Ade), histidine (His) and β-galactosidase (LacZ) reporter genes was tested to validate the interaction. dsRBD, double-stranded RNA binding domain; DUF283, domain of unknown function 283; PAZ, Piwi-Argonaute-Zwille; RIII, ribonuclease III.