Figure 1.

Unsupervised hierarchical clustering of samples from sepsis (“se” for elderly and “sa” for adults) and healthy controls (“ce” for elderly and “ca” for adults) based on long noncoding RNA (lncRNA) expression. Expression measurements from the top 5% more variable lncRNAs (based on their coefficient of variation across all samples) were used to group samples using UPGMA clustering and Pearson correlation as a distance measurement. Samples are labeled according to disease status (sepsis in red, healthy controls in blue) and age (elderly subjects are shown in darker colors whereas those from young adults are shown in lighter colors).