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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Am J Sports Med. 2017 May 25;45(11):2637–2646. doi: 10.1177/0363546517706138

Figure 2.

Figure 2

Osteogenic gene transcript expression of human amnion-derived mesenchymal stromal cells and epithelial cells (hAMSCs and hAECs) and human adipose-derived stromal cells (hADSCs). Gene transcript expression levels of (A) runx-2 and (B) osteocalcin (OCN) in hAEC, mixed (hAEC + hAMSC co-culture), and hAMSC groups relative to hADSCs (dotted line) cultured in basal medium. (C) Runx-2 and (D) osteocalcin expression of amnion-derived mesenchymal stromal cell groups cultured in osteogenic differentiation medium compared with respective expression levels in hADSCs cultured at the same time points (n = 4 per group per time point). Lines indicate statistical difference (P < .05) between connected groups. *Statistical differences compared with the hADSC group at the same time point (P < .05).