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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Am J Sports Med. 2017 May 25;45(11):2637–2646. doi: 10.1177/0363546517706138

Figure 4.

Figure 4

Chondrogenic gene transcript expression of human amnion-derived mesenchymal stromal cells and epithelial cells (hAMSCs and hAECs) and human adipose-derived stromal cells (hADSCs). Transcript expression levels of (A) Sox-9 and (B) aggrecan in hAEC, mixed (hAEC + hAMSC co-cultured), and hAMSC groups relative to hADSCs (dotted line) cultured in basal medium. (C) Sox-9, (D) aggrecan, and (E) runx-2 expression of amnion mesenchymal stromal cell groups cultured in chondrogenic differentiation medium compared with respective expression levels in hADSCs cultured at the same time points (n = 4 per group per time point). Lines indicate statistical difference (P < .05) between connected groups. *Statistical differences compared with the hADSC group at the same time point (P < .05).