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. 2018 Feb 14;2018:5180165. doi: 10.1155/2018/5180165

Figure 5.

Figure 5

HACE suppressed the expression of TIMP-2 in kidney. (a) The expression of TIMP-2 by immunohistochemistry. Bar = 100 μm. (b) The expression of TIMP-2 by Western blot. GAPDH was shown as a loading control. The relative expression was the ratio of TIMP-2 to GAPDH conducted by densitometric analysis. Con: nondiabetic control group; DN: streptozotocin-induced diabetic group; HACE-L: low-dose-HACE-treated group; HACE-H: high-dose-HACE-treated group; Bena: benazepril. ∗∗P < 0.01 versus Con; ▲▲P < 0.01 versus DN; ##P < 0.05 versus Bena.