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. 2018 Feb 26;8:3640. doi: 10.1038/s41598-018-21912-x

Table 1.

General characteristics of 19 included cross-sectional studies.

Study Country Objective Respondents Recruitment site Sample size (response rate %) Results obtained NOS Score
Primary outcome Secondary outcome
Charakorn C. et al.23 Thailand Evaluation of knowledge about the Pap smear, HPV, and the HPV vaccine, and the acceptability of the vaccine to Thai women Both mothers and their daughters Hospital 536 (70%) Poor knowledge of HPV infection and HPV vaccine Positive intention for 77% and 84% of mothers and daughters, respectively 5
Choi HCW et al.11 Hong Kong To provide a more representative and updated assessment on the acceptability of female adolescent HPV vaccination in Hong Kong Schoolgirls aged between 11 and 18 years old, and mothers with daughter(s) ≤ 18 years old Schoolgirls from 5 constituency areas and mothers through random-digit dialling telephone interviewing Total of 1022 (39.3%) and 1005 (50.2%) mothers in 2008 and 2012 respectively. 2167 (96.2%) for schoolgirls’ survey 27.5% and 37.6% of mothers intended to vaccinate daughters’ in 2008 and 2012, respectively. 27.1% of schoolgirls in 2008. Willingness to pay for full course of vaccination 6
Egawa-Takata T et al.13 Japan To investigate why Japanese adolescent girls decline, continue or discontinue their HPV vaccination, how their mothers influence their decisions, and the mothers’ feelings about future HPV vaccination for their daughters Mothers with daughters aged 10–18 Internet 2828 mothers (28.3%) Mothers’ knowledge about HPV vaccine and attitude towards cervical cancer screening influenced their decision to get their daughters vaccinated 16% intended to get daughters vaccinated 5
Egawa-Takata T et al., 201612 Japan To investigate the prevalence of use of HPV vaccination in the daughters of obstetricians and gynecologists, and their attitudes related to the HPV vaccine and cervical cancer screening, to gain insights into their reasoning for or against recommending HPV vaccination for their daughters Doctors’ daughters: HPV vaccinations before (2012) and after (2014) the adverse news releases Hospital 264 (46%) The number of vaccinated daughters was lower in 2014 than in 2012 64% intended to get daughters vaccinated 1
Gu C et al.8 China To examine young women’s perceptions and acceptability of human papillomavirus vaccination and factors influencing acceptability in mainland China Undergraduate female students year 1 to 4, aged 18 or above Medical college 119 (94.3%) 44% of women intended to get vaccinated Low awareness and knowledge of HPV vaccine and cervical cancer 7
Hsu YY et al.16 Taiwan To examine health beliefs and intention to obtain HPV vaccination among undergraduate women in Taiwan Full-time female undergraduate students attending 5 universities in Taiwan Five universities in Taiwan 845 Poor awareness of HPV infection and HPV vaccine 63% of students intended to obtain HPV vaccine 7
Johnson DC et al.22 Nepal Assessing knowledge and awareness of HPV, cervical cancer and HPV vaccines among rural and suburban women in Nepal Women attending health camps Khokana, a suburban community, and Sanphebagar, a rural community 749 Poor awareness and knowledge of HPV, cervical cancer and HPV vaccine 77.5% of women intended to obtain HPV vaccine if offered for free 6
Juntasopeepun P et al.24 Thailand To examine knowledge and beliefs regarding HPV and cervical cancer and to predict vaccination intention among young women in Thailand Thai women aged 18–24 years in Chiang Mai, Thailand University 391 56.5% intended to receive the vaccine Knowledge about HPV and cervical cancer were moderate 7
Kang HS et al.14 Korea To examine the relationships between attitudes toward and intention to receive the HPV vaccination and intention to use condoms among Korean female college students Female Korean college students Sixteen colleges located in 16 regions across the nation 1600 (87%) Intention to get vaccinated was not high, and women were not confident of the vaccine’s safety and changes in sexual behaviour Intention gets lower when attitude is negative 5
Kang HY et al.15 Korea To examine knowledge about HPV and attitudes towards HPV and HPV vaccination among Korean female undergraduate students Female undergraduate students University 339 (94.7%) Awareness and knowledge of HPV was poor Wanting more education about the vaccine, perceived severity and knowledge of HPV associated with intention 6
Kruiroongroj S et al.25 Thailand To evaluate the willingness of Thai mothers to get their daughters vaccinated against HPV if it is free of charge (acceptance) or if it is not free of charge (willingness to pay), and to examine their current knowledge regarding HPV vaccine and cervical cancer Female parents of adolescent girls aged 12–15 Secondary schools 1200 (71.7%) Knowledge regarding the HPV vaccine was low 76.9% of parents intended to get vaccinated if offered for free and 68.9% were willing to pay if vaccine was not offered for free 3
Li J et al.9 China To assess women’s knowledge about HPV and their acceptance of the vaccines Women aged 14–59 living in metropolitan and rural regions of China 6 community clusters from 3 major cities and rural areas in 3 provinces 6024 (95.8) Knowledge and awareness were low among women in both metropolitan and rural areas 84.6% of women intended to get vaccinated if the HPV vaccine was made available to them 7
Montgomery MP et al.21 India To assess the knowledge, acceptability, attitudes and feasibility concerning HPV and cervical cancer among adult women in Dakshina Kannada district of the southern state of Karnataka, India All women between the ages of 18 and 44 Family practice and obstetrics and gynaecology clinics and postnatal wards within the hospital Karnataka, India 225 (90%) Knowledge and awareness related to HPV and cervical cancer was low 46% intended to receive the HPV vaccine 5
Sam IC et al.19 Malaysia To determine the acceptability rates of HPV vaccination by Malaysian mothers for daughters Mothers with at least one child under 18 years old attending outpatient clinics University hospital 362 65.7% and 55.8% of mothers intended to get daughters and sons vaccinated, respectively Knowledge of HPV and the HPV vaccine was low 5
Wong LP20 Malaysia To assess the knowledge and attitudes towards HPV, HPV vaccination and cervical cancer among young women in rural settings Women aged between 18 and 25 years and living in the household Rural villages in the states of Perak and Pahang in Peninsular Malaysia 589 (84.7%) Knowledge of HPV, HPV vaccination and cervical cancer were extremely poor Two thirds of respondents professed an intention to receive the HPV vaccine 4
Yen CF et al.17 Taiwan To explore awareness and acceptability of HPV vaccination and to identify factors influencing HPV acceptability among women with physical disabilities in Taiwan Adult women aged 18–69 who were officially registered as having physical disabilities in Taipei City as of March 2009 As a part of a larger study on reported history of Pap smear tests, health experiences, perceptions of cervical cancer and HPV vaccination among women with physical disabilities in Taiwan. 438 Awareness of HPV vaccine was poor Only 3.2% intended to obtain the vaccine. Intention increased up to 60% if the vaccine was offered for free 4
Young AM et al.26 Philippines To examine attitudes toward and acceptability of HPV vaccination among a community-based sample of women in the Philippines Women aged from 18 to 52 years old Three communities in the Central Visayan region 435 54% intended to receive HPV vaccine at low price, whereas only 30% and 31% intended to receive at moderate and high prices, respectively Mothers and partners were influential in vaccination decisions together with access to transportation, social support and benefits of vaccination 4
Yu Y et al.10 China To investigate awareness and knowledge of HPV/the HPV vaccine and potential acceptance of the HPV vaccine among mothers with a teenage daughter in Weihai, Shandong, China Mothers of daughters aged 9–17 years old Weihai, China 1578 (85.3%) Awareness and knowledge of HPV/HPV vaccine was poor Only 26.49% of mothers intended to get their daughters vaccinated 5
Zhuang QY et al.18 Singapore To describe the knowledge, attitudes and practices of young women regarding HPV vaccination Female students attending a tertiary institution in Singapore University 255 Among the unvaccinated participants (n = 230), 41.7% had no intention to receive the vaccine and 27.0% cited lack of information as a major barrier to HPV vaccination Knowledge of HPV and cervical cancer was found to be low 6