Table 3.
Cox proportional hazard regression analysis of patients' overall survival.
| Variables | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age (≤54/>54) | 1.698 (0.860–3.354) | 0.127 | ||
| Gender (F/M) | 0.551 (0.282–1.075) | 0.080 | ||
| Tumor location (pyloric/nonpyloric antrum) | 1.130 (0.580–2.204) | 0.719 | ||
| HER-2 (positive/negative) | 1.818 (0.698–4.736) | 0.221 | ||
| RDW (≤13.4%/>13.4%) | 3.497 (1.713–7.140) | 0.001 | ||
| WBC (≤5.69/>5.69 g/L) | 2.165 (1.084–4.324) | 0.029 | 1.323 (0.584–2.997) | 0.502 |
| MO (≤0.42/>0.42 g/L) | 2.125 (1.067–4.232) | 0.032 | 1.205 (0.521–2.790) | 0.663 |
| NLR (≤2.755/>2.755) | 6.482 (3.131–13.418) | <0.001 | ||
| CA125 (≤26.6/>26.6 U/mL) | 2.241 (1.128–4.453) | 0.021 | 1.858 (0.924–3.734) | 0.082 |
| CA199 (≤11.9/>11.9 U/mL) | 1.479 (0.761–2.872) | 0.248 | ||
| CEA (≤2.4/>2.4 μg/L) | 1.513 (0.773–2.961) | 0.227 | ||
| RDW + NLR | 3.252 (1.289–8.203) | <0.001 | 3.197 (1.248–8.191) | <0.001 |
HR: hazard ratio; CI: confidence interval; RDW + NLR: combination of red blood cell distribution width and neutrophil-to-lymphocyte ratio. P less than 0.05 is statistically significant. Univariate and multivariate analysis performed using Cox proportional hazards models. Multivariate analyses using the 5 significant variables (age, WBC, MO, CA125, and RDW + NLR, except RDW and NLR) above were performed. Significant factors in univariate and multivariate analysis are indicated in bold.