Table 3.
Genetic models | Unadjusted | Adjusteda | Adjustedb | |||
---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
Additive | 0.69 (0.55–0.86) | <0.001 | 0.66 (0.52–0.83) | <0.001 | 0.68 (0.52–0.88) | 0.004 |
Recessive | 0.33 (0.18–0.62) | <0.001 | 0.33 (0.17–0.65) | 0.001 | 0.28 (0.14–0.60) | 0.001 |
Dominant | 0.72 (0.55–0.95) | 0.018 | 0.67 (0.50–0.90) | 0.008 | 0.73 (0.53–1.01) | 0.059 |
GA versus GG | 0.83 (0.63–1.10) | 0.201 | 0.77 (0.57–1.05) | 0.097 | 0.87 (0.62–1.23) | 0.43 |
AA versus GG | 0.31 (0.17–0.58) | <0.001 | 0.30 (0.15–0.60) | <0.001 | 0.27 (0.13–0.58) | <0.001 |
Allele (A versus G) | 0.69 (0.55–0.86) | <0.001 |
CI: confidence interval; DN: diabetic nephropathy; OR: odds ratio. aAdjusted for age and sex. bAdjusted for age, sex, Hcy, BMI, duration of diabetes, hypertension, smoking, total cholesterol, and TG levels.