Table 1. Profile of geographic regions included in the CIPHER global cohort adolescent analysis (N = 38,187 adolescents).

Region	Countries included	Number of study centers	Number of adolescents (%)	Observation period	Year of birth median (IQR)	Duration of adolescent follow-up (from age 10 years) median (IQR) years
Europe	Belgium, France, Ireland, Italy, Netherlands, Poland, Portugal, Romania, Russian Federation, Spain, Sweden, Switzerland, Ukraine, United Kingdom	153	3,054 (8.0)	1982–2015	1995 (1991–1999)	6.4 (3.6–8.0)
North America	United States of America	117	1,032 (2.7)	1991–2014	1994 (1992–1996)	3.7 (2.0–5.4)
South and Southeast Asia	Cambodia, India, Indonesia, Malaysia, Myanmar, Thailand, Vietnam	73	2,902 (7.6)	1994–2014	2001 (1999–2002)	2.5 (1.2–4.4)
South America and the Caribbean	Argentina, Brazil, Haiti, Honduras	6	903 (2.4)	1990–2015	1998 (1995–2000)	5.0 (2.7–7.5)
Sub-Saharan Africa	Benin, Botswana, Burkina Faso, Burundi, Cameroon, Central African Republic, Democratic Republic of Congo, Côte d’Ivoire, Ethiopia, Ghana, Guinea, Kenya, Lesotho, Malawi, Mali, Mozambique, Rwanda, Senegal, South Africa, Swaziland, Tanzania, Togo, Uganda, Zambia, Zimbabwe	565	30,296 (79.3)	1996–2015	2000 (1999–2002)	2.1 (0.9–3.8)
Total		914	38,187	1982–2015	2000 (1998–2002)	3.1 (1.5–5.2)

Abbreviations: CIPHER, Collaborative Initiative for Paediatric HIV Education and Research; IQR, interquartile range.