Table 2. Cox proportional hazard analysis of ESBL-PE acquisition.
Variable | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
Person-days | Crude HRa [95% CIb] | Pc | Adjusted HR [95% CI] | p | |
Low birth weight | 0.01 | 0.01 | |||
No (> = 2500gr) | 5300 | Ref.d | Ref. | ||
Yes (<2500gr) | 324 | 2.6 [1.2; 5.5] | 2.7 [1.2 ; 5.9] | ||
Maternal job | 0.21 | ||||
No Job | 3900 | Ref. | |||
Manual job | 1500 | 1.0 [0.6; 1.9] | |||
Office job | 199 | 2.5 [1.0; 6.5] | |||
Latrine type | 0.41 | ||||
Outside without flush | 5100 | Ref. | |||
Outside with flush | 137 | 0.7 [0.1; 5.4] | |||
Inside without flush | 176 | 0.5 [0.1; 3.8] | |||
Inside with flush | 232 | 2.1 [0.9; 5.3] | |||
Habitat type | 0.46 | ||||
Room shared with other household | 4389 | Ref. | |||
House shared with other household | 500 | 0.8 [0.4; 1.4] | |||
Individual house | 410 | 1.3 [0.2; 2.5] | |||
Number of rooms | 0.63 | ||||
1 room | Ref. | ||||
2 rooms and more | 1.1 [0.6; 1.9] | ||||
Number of household members | 0.16 | ||||
Less than 5 members | 4500 | Ref. | |||
5 members and more | 1097 | 1.01 [0.5; 1.7] | |||
Animal ownership | 0.32 | ||||
No | 5370 | Ref. | |||
Yes | 214 | 1.7 |0.2; 10.6] | |||
Site | 0.19 | 0.96 | |||
Semi-rural site | 4100 | Ref. | Ref. | ||
Urban site | 1500 | 1.4 [0.8; 2.5] | 1.0 [0.5; 1.8] | ||
Mode of delivery | <0.001 | 0.001 | |||
Vaginal delivery | 5300 | Ref. | Ref. | ||
Cesarean | 320 | 3.5 [1.8; 6.8] | 3.4 [1.7 ; 7.1] | ||
Supervising person at delivery | 0.14 | ||||
Non medical staff | 1700 | Ref. | |||
Medical staff | 3800 | 1.6 [0.8 ; 2.9] | |||
Maternal ESBL-carriage | 0.06 | 0.09 | |||
No | 4000 | Ref. | Ref. | ||
Yes | 1100 | 1.7 [1.0 ; 3.0] | 1.6 [0.9 ; 2.9] | ||
Antibiotic during delivery | 0.04 | 0.04 | |||
No | 5200 | Ref. | Ref. | ||
Yes | 423 | 2.1 [1.0; 4.2] | 2.2 [1.1; 4.5] | ||
Place of delivery | 0.09 | ||||
Home | 2600 | Ref. | |||
Health-care facilities | 3000 | 1.6 [0.9 ; 2.7] | |||
Hospitalization during the first month of life | 0.23 | ||||
No | 5500 | Ref. | |||
Yes | 84 | 2.7 |0.62; 11.2] | |||
Antibiotics intake during the first month of life | 0.54 | ||||
No | 5500 | Ref. | |||
Yes | 58 | 2.0 [0.27;14.7] |
aHR, Hazard Ratio
b95% CI, 95% Confidence Interval
cp, p-value
dRef., reference.