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. 2018 Mar 1;13(3):e0193325. doi: 10.1371/journal.pone.0193325

Table 2. Cox proportional hazard analysis of ESBL-PE acquisition.

Variable Univariate analysis Multivariate analysis
Person-days Crude HRa [95% CIb] Pc Adjusted HR [95% CI] p
Low birth weight 0.01 0.01
No (> = 2500gr) 5300 Ref.d Ref.
Yes (<2500gr) 324 2.6 [1.2; 5.5] 2.7 [1.2 ; 5.9]
Maternal job 0.21
No Job 3900 Ref.
Manual job 1500 1.0 [0.6; 1.9]
Office job 199 2.5 [1.0; 6.5]
Latrine type 0.41
Outside without flush 5100 Ref.
Outside with flush 137 0.7 [0.1; 5.4]
Inside without flush 176 0.5 [0.1; 3.8]
Inside with flush 232 2.1 [0.9; 5.3]
Habitat type 0.46
Room shared with other household 4389 Ref.
House shared with other household 500 0.8 [0.4; 1.4]
Individual house 410 1.3 [0.2; 2.5]
Number of rooms 0.63
1 room Ref.
2 rooms and more 1.1 [0.6; 1.9]
Number of household members 0.16
Less than 5 members 4500 Ref.
5 members and more 1097 1.01 [0.5; 1.7]
Animal ownership 0.32
No 5370 Ref.
Yes 214 1.7 |0.2; 10.6]
Site 0.19 0.96
Semi-rural site 4100 Ref. Ref.
Urban site 1500 1.4 [0.8; 2.5] 1.0 [0.5; 1.8]
Mode of delivery <0.001 0.001
Vaginal delivery 5300 Ref. Ref.
Cesarean 320 3.5 [1.8; 6.8] 3.4 [1.7 ; 7.1]
Supervising person at delivery 0.14
Non medical staff 1700 Ref.
Medical staff 3800 1.6 [0.8 ; 2.9]
Maternal ESBL-carriage 0.06 0.09
No 4000 Ref. Ref.
Yes 1100 1.7 [1.0 ; 3.0] 1.6 [0.9 ; 2.9]
Antibiotic during delivery 0.04 0.04
No 5200 Ref. Ref.
Yes 423 2.1 [1.0; 4.2] 2.2 [1.1; 4.5]
Place of delivery 0.09
Home 2600 Ref.
Health-care facilities 3000 1.6 [0.9 ; 2.7]
Hospitalization during the first month of life 0.23
No 5500 Ref.
Yes 84 2.7 |0.62; 11.2]
Antibiotics intake during the first month of life 0.54
No 5500 Ref.
Yes 58 2.0 [0.27;14.7]

aHR, Hazard Ratio

b95% CI, 95% Confidence Interval

cp, p-value

dRef., reference.