Table 2. Univariate analysis for sickle cell maculopathy.
| Factors | Sickle maculopathy present | Sickle maculopathy absent | p value |
|---|---|---|---|
| Gender (female) | 62% | 24% | 0.0610 |
| Age (y) | 39.8 | 38.7 | 0.7568 |
| Ethnicity (white) | 46% | 71% | 0.3891 |
| SCD type | |||
| SS | 38% | 71% | 0.2300 |
| SC | 38% | 24% | |
| Sb | 23% | 6% | |
| Transfusions (Y) | 61% | 94% | 0.0123 |
| Chelation (Y) | 8% | 59% | 0.0076 |
| Oncocarbide (N) | 77% | 41% | 0.0711 |
| Splenectomy (N) | 46% | 41% | 1.0000 |
| Ischemic events status (N) | 62% | 53% | 0.7273 |
| HbF (%) | 5.2 | 15.0 | 0.0278 |
| HbS (%) | 67.3 | 56.7 | 0.1321 |
| Reticulocytes (%) | 0.225 | 0.245 | 0.6652 |
| Leucocytes (%) | 7.3 | 8.8 | 0.1105 |
| Neutrophils (%) | 3.6 | 5.1 | 0.0364 |
| Hemoglobin (g/dL) | 9.9 | 9.6 | 0.6379 |
| Hematocrit (%) | 28.4 | 27.9 | 0.7980 |
| LDH (U/L) | 328.1 | 358.5 | 0.5492 |
| Urea (mg/dL) | 26.3 | 28.9 | 0.7319 |
| Uric acid (mg/dL) | 5.7 | 4.6 | 0.0462 |
| Bilirubin-tot (mg/dL) | 1.8 | 2.3 | 0.1932 |
| Bilirubin-direct (mg/dL) | 0.61 | 0.71 | 0.2612 |
| AST (U/L) | 36.7 | 42.5 | 0.6032 |
| ALT (U/L) | 26.1 | 38.4 | 0.4017 |
| Ferritin (ng/mL) | 341.9 | 1306 | 0.0346 |
| Transferrin saturation (%) | 25.0 | 48.0 | 0.0038 |
| MCV (fL/red cell) | 73.5 | 78.5 | 0.2210 |
| Platelets (GI/L) | 288.4 | 369.5 | 0.1958 |
| Creatinine (mg/dL) | 0.80 | 0.72 | 0.6041 |
SCD, sickle cell disease; LDH, lactate dehydrogenase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; MCV, mean corpuscular volume