Table 2. Homozygous and heterozygous inheritance of shared HLA class II epitopes associated with type 1 diabetes.
| Locus | Genotype | P corr value | OR |
|---|---|---|---|
| HLA-DRB1 | Q70+/Q70+ | 1.4x10-17 | 20.1 |
| Q70+/Q70- | 5.0x10-15 | 10.2 | |
| D70+/D70- | 1.8x10-7 | 0.27 | |
| D70+/D70+ | 6.1x10-10 | 0.11 | |
| R70+/R70- | 9.44x10-13 | 0.04 | |
| K71+/K71- | 2.6x10-12 | 5.5 | |
| R71+/R71- | 4.7x10-5 | 0.2 | |
| R71+/R71+ | 3.9x10-9 | 0.1 | |
| E74+/E74- | 3.4x10-7 | 0.16 | |
| HLA-DQB1 | L26+/L26+ | 4.3x10-21 | 45.8 |
| L26+/L26- | 3.9x10-19 | 14.9 | |
| G26+/G26+ | 8.68x10-6 | 0.11 | |
| A57+/A57+ | 1.25x10-24 | 100.6 | |
| A57+/A57- | 5.61x10-23 | 17.5 | |
| D57+/D57- | 4.8x10-22 | 0.08 | |
| D57+/D57+ | 3.94x10-9 | 0.03 | |
| R70+/R70+ | 1.3x10-10 | 17.6 | |
| R70+/R70- | 2.8x10-8 | 10.4 | |
| G70+/G70- | 1.3x10-6 | 0.31 | |
| G70+/G70+ | 2.3x10-8 | 0.08 | |
| HLA-DQA1 | L69+/L69+ | 1.07x10-12 | 22.86 |
| L69+/L69- | 2.69x10-8 | 8.82 |