. 2018 Mar 1;13(3):e0193684. doi: 10.1371/journal.pone.0193684

Table 3. Linkage disequilibrium of DR/DQ susceptibility epitopes in type 1 diabetes patients and control subjects.

HLA class II susceptibility epitopes	Patients (%) (N = 170)	Control subjects (%) (N = 192)	P Value	OR (95% CI)	LD in patients P value (OR)	LD in controls P value (OR)
DRβ Q⁷⁰⁺/DQβ A⁵⁷⁺	153 (90)	57 (29.7)	≤ 0.0001	21.3 (11.8–38.4)	0.001 (20.5)	1.80x10^-6 (4.9)
DRβ Q⁷⁰⁺/DQβ A^57-	5 (2.9)	40 (20.8)	≤ 0.0001	0.1 (0.04–0.3)
DRβ Q^70-/DQβ A⁵⁷⁺	7 (4.1)	21 (10.9)	0.02	0.35 (0.14–0.84)
DRβ Q^70-/DQβ A^57-	5 (2.9)	74 (38.5)	≤ 0.0001	0.05 (0.02–0.12)

n (%) p value Fisher exact test