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. 2018 Mar 1;13(3):e0193684. doi: 10.1371/journal.pone.0193684

Table 8. Extended haplotype of class II risk epitopes in type 1 diabetes patients and control subjects.

HLA class II Genotype Patients (%) (N = 182) Control subjects (%) (N = 192) P value OR 95% CI
DRB Q 70- DQB L26A57 DQA Y11R52R55F61T64I66L69V/L76H129E/K175/ X 103 (57%) 48 (25%) <0.0001 3.8 2.5–5.9
DRB Q 70—DQB L26A57 DQA Y11R52R55F61T64I66L69V/L76H129E/K175/ DRB Q 70—DQB L26A57 DQA Y11R52R55F61T64I66L69V/L76H129E/K175 64 (35%) 3 (2%) <0.0001 34.2 10.5–111.2
X / X (non-risk) 15 (8%) 141 (73%) <0.0001 0.03 0.02–0.06