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. 2018 Mar 1;13(3):e0193609. doi: 10.1371/journal.pone.0193609

Fig 6. Effects of miR-124 NPs on levels of pro-inflammatory cytokines in the ischemic territory and serum.

Fig 6

(A-D) Levels of IFN-γ, IL-1β, IL-6 and TNF-α in the ischemic territory (infarct core and adjacent peri-infarct tissue) 2 days following PT. (E-H) Serum levels of the above mentioned cytokines from the same animals. Data are shown as mean ± SEM with the following number of animals included in each experimental group: sham n = 10, PT saline n = 4, PT void NPs n = 4, PT scramble-miR NPs n = 3, PT miR-124 NPs n = 4. ** indicates p < 0.01 and *** indicates p < 0.001 versus sham group, ## indicates p < 0.01 versus all other experimental conditions after PT. Abbreviations: NPs, nanoparticles; PT, photothrombosis.