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. 2018 Jan 17;9(3):390–399. doi: 10.1111/1759-7714.12593

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© 2018 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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BarH‐like homeobox 2 (Barx2) inhibits aerobic glycolysis through suppressing the Wnt/β‐catenin signaling pathway. (a) The lactate dehydrogenase (LDH) activity, glucose utilization, lactate production, and intracellular adenosine triphosphate (ATP) level were detected in different groups including mock, control, pBarx2, and pBarx2 + LiCl. (b) The LDH activity, glucose utilization, lactate production, and intracellular ATP level were detected in human bronchial epithelium cell line (HBE) cells after transfecting of control vector or siBarx2. *P < 0.05.