Skip to main content
. Author manuscript; available in PMC: 2018 Mar 2.
Published in final edited form as: Mucosal Immunol. 2017 Aug 30;11(2):486–495. doi: 10.1038/mi.2017.67

Figure 1. Overview schematic of the clinical trial.

Figure 1

Ten subjects were recruited into each of the groups A–F, randomized in a double blind fashion to receive PO vs ID vs PO+ID Danish BCG. An additional 8 subjects were recruited into an open label, ID Connaught BCG vaccination cohort (to compare ID immunity induced by Danish vs Connaught BCG). During year 1 of the trial, groups A and B were identical (given only ID BCG), groups C and D were identical (given only PO BCG), and groups E and F were identical (given both ID and PO BCG). Blood, tear, nasal wash and stool samples were collected at 9 different time points (pre-vaccination, and 1 week, 2 months, 6 months, 12 months, 12 months plus 1 week, 14 months, 18 months and 24 months post-vaccination).

*10 volunteers/group