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. Author manuscript; available in PMC: 2018 Mar 2.
Published in final edited form as: Mucosal Immunol. 2017 Aug 30;11(2):486–495. doi: 10.1038/mi.2017.67

Figure 5. Bronchoalveolar lavage (BAL) sub-study to identify lung TB-specific T cells.

Figure 5

A sub-study targeting subjects enrolled in the parent DMID-01-351 trial was conducted involving a single post-vaccination BAL procedure and blood sample obtained the same day. Panels A. and B. show IFN-γ ELISPOT results for PBMC and BAL cells, respectively. Box-plots with scatter plot overlay are presented for PBMC and BAL cells. Panel C. shows flow cytometric studies identifying the percentages of CD4+ and CD8+ T cells expressing α4β1 in PBMC. Panel D. shows flow cytometric studies identifying the percentages of CD4+ and CD8+ T cells expressing CXCR3 among BAL cells. *p<0.05 by Mann-Whitney testing compared with group responses.