Table 4.

Operating Characteristics comparing the three response models using continuous doses

		True MTD
		−0.16			0.52			1.22
Response ρ0		(B)	Logistic	(A)	(D)	Logistic	(C)	(F)	Logistic	(E)
Safety	Average % DLTs	45.000	45.900	47.800	33.600	34.100	33.500	28.200	28.200	26.600
	% trials w. DLT rate > θ + 0.1	72.1	79.0	89.2	4.0	4.7	6.9	0.3	0.1	0.1
Efficiency	Average MTD	−0.018	−0.058	−0.116	0.519	0.519	0.556	1.211	1.212	1.1246
	Average bias	0.139	0.099	0.041	−0.001	−0.001	0.036	−0.005	−0.004	−0.091
	RMSE	0.225	0.128	0.064	0.082	0.105	0.199	0.122	0.150	0.307
% trials: MTD estimate is in	(γ − 0.10, γ + 0.10)	42.1	56.7	87.3	78.9	66.3	37.6	62.0	49.4	16.9
	(γ − 0.15, γ + 0.15)	56.6	72.9	96.7	93.1	84.8	55.4	77.6	67.2	24.7
	(γ − 0.15γ, γ + 0.15γ)	7.9	16.3	35.3	66.8	55.0	29.0	85.7	74.5	28.6
	(γ − 0.20γ, γ + 0.20γ)	10.7	21.0	45.4	81.2	68.5	39.4	94.3	87.8	46.9