Table 2.
Study phase | Mode of delivery | Cell type | Time from onset | Primary Outcome measure | Secondary Outcome measure | Clinical identifier |
---|---|---|---|---|---|---|
I | IC | CTX0E03 neural stem | 6 mo–5 year | safety | Function outcome | NCT01151124 |
I/II | IC | Modified stem, SB623 | 6–12 mo | safety | Function outcome | NCT01287936 |
II | IC | Autologous peripheral CD34+ stem | >6 mo, <60 mo | Function outcome | Function outcome; Imaging | NCT00950521 |
I | IV; IT | Umbilical cord, mesenchymal | IV, 7–14 d; IT, | Function outcome | Function outcome; MRI changes | NCT01389453 |
I/IIa | IV | Autologous bone marrow mononuclear | 24–72 h | Safety; Feasibility | Function outcome | NCT00859014 |
I/IIa | IV | Autologous mesenchymal stem | Within 6 wk | Safety; Feasibility | Function outcome | NCT00875654 |
I/II | IA | Autologous bone marrow CD 34 + stem | 7 d | safety | Function outcome | NCT00535197 |
Abbreviations: IA=intra-arterial; IC=intracerebral; IT=intrathecal.