Table 1.

Echocardiography measurements of cardiac function in LAD/reperfused hearts.

Parameter	WT	Diaph1-/-	P value
Pre LAD/reperfusion
Heart rate (beats/min)	556 ± 63	532 ± 46	NS
LV ESD (mm)	1.81 ± 0.1	1.78 ± 0.2	NS
LV EDD (mm)	2.8 ± 0.2	2.9 ± 0.3	NS
LV mass (mg)	98 ± 14	116 ± 18	NS
Cardiac output (ml/min)	10.6 ± 2.1	11. ± 1.9	NS
Stroke volume (ml/min)	19.8 ± 2.2	24.5 ± 3.6	NS
LV thickness at end systole (mm)	1.44 ± .32	1.54 ± 0.36	NS
Post LAD/reperfusion (48 h after reperfusion)
Heart rate (beats/min)	496 ± 28	502 ± 35	NS
LV ESD (mm)	3.6 ± 0.4	2.2 ± 0.3	< 0.05
LV EDD (mm)	4.1 ± 0.5	3.3 ± 0.2	< 0.05
LV mass (mg)	112 ± 19	121 ± 22	NS
Cardiac output (ml/min)	12.6 ± 1.5	17.8 ± 2.6	< 0.05
Stroke volume (ml/min)	21.3 ± 4.8	36.4 ± 2.9	< 0.05
LV wall thickness at end systole(mm)	1.38 ± 0.24	1.41 ± 0.19	NS

LVESD: left ventricular end systolic diameter, LVEDD: left ventricular end diastolic diameter, n = 10/group.