Table 2.
Brain region volumes (mm3) (adjusted for sex, age, and eTIV) in the absence and presence of DRB1*13:02.
| Brain region | DRB1*13:02 Absent |
DRB1*13:02 Present |
||
|---|---|---|---|---|
| Mean | SEM | Mean | SEM | |
| Cerebellum Gray Mattera | 78,116.5 | 1000.8 | 85,657.3 | 2497.6 |
| Brainstema | 21,540.1 | 230.7 | 22,537.6 | 575.8 |
| Thalamusa | 14,198.0 | 160.4 | 14,554.4 | 400.3 |
| Caudatea | 7003.6 | 112.5 | 7411.2 | 280.8 |
| Putamena | 9839.5 | 139.6 | 9811.5 | 348.4 |
| Accumbensa | 1088.4 | 19.5 | 1122.4 | 48.7 |
| Palliduma | 2750.9 | 45.9 | 2851.1 | 114.7 |
| Amygdalaa | 3278.0 | 49.1 | 3239.9 | 122.6 |
| Diencephalona | 7421.6 | 80.2 | 7552.5 | 200.1 |
| Total Subcorticalb | 145,236.5 | 1270.9 | 154,738.0 | 3171.7 |
a
Statistics from a repeated measures ANCOVA where the 9 regions were the Within-Subjects factors, the absence or presence of DRB1*13:02 was the Between-Subjects factor, and sex, age and eTIV were covariates.
b
Statistics from a univariate ANCOVA where the subcortical volume was the dependent variable, the absence or presence of DRB1*13:02 was a fixed factor, and sex, age and eTIV were covariates.