Fig. 5.

Plasma concentrations of Nexvax2 peptides. Plasma concentrations of NPL001, NPL002, and NPL003 peptides at 45 min after intradermal administration of Nexvax2 in cohort 3 (n = 10). Mean (95% CI) concentrations are shown for NPL001 (A), NPL002 (B), and NPL003 (C) after escalating doses of Nexvax2, and at the maintenance dose of 900 μg. The lower level of quantitation (LLOQ) for each peptide was 2 ng/mL indicated by the dashed line; readings below the LLOQ were assigned 2 ng/mL. Pre-treatment plasma concentrations of Nexvax2 peptides were below the LLOQ for each of the indicated doses in all participants.