Search	Search strings	No. of articles
#1	Search "Breast Neoplasms"[Mesh] OR “Breast Neoplasm” OR “Breast Cancer” OR “Breast Carcinoma” OR “Breast Tumor*” OR “Neoplasm*, Breast” OR “Tumor*, Breast” OR “mammary carcinoma” OR “mammae cancer” OR “mammary cancer” OR “carcinoma mammae”	322520
#2	Search "Bone metastases" OR "Bone metastasis" OR "metastasis of Bone" OR "metastases of Bone" OR “Skeletal metastases” OR “Skeletal metastasis” OR “Skeletal complication*” OR “skeletal-related event*”	44143
#3	Search #1 AND #2	8664
#4	Search #3 NOT (Clinical trial* [pt] OR Bibliography [pt] OR Comment [pt] OR Historical Article [pt] OR Interview [pt] OR Review [pt] OR Letter [pt] OR Newspaper Article [pt] OR Case Report* OR Books and Documents [pt] OR Clinical Study [pt] OR Guideline [pt] OR Systematic Review* [pt])	5429
#5	Search #4 Limits: Humans, English	3781
#6	Search #5 Limits: Publication Date from January 1st, 2000 to June 11, 2017	2314