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. 2018 Mar 1;8:3901. doi: 10.1038/s41598-018-22206-y

Table 5.

Urinary tDON and tDOM-1 by gender and age groups.

Compound Positive Mean (± SD) Median Range
n (%) ng mL−1 ng mL−1 ng mL−1
Gender Male, n = 56
tDON 56 (100%) 38.8 (±32.2) 29.8 3.11–132
fDON 49 (87.5%) 5.96 (±6.03) 4.25 ND–25.2
tDOM-1 14 (25.0%) 0.37 (±1.08) 0.05 ND–6.43
Female, n = 95
tDON 95 (100%) 52.8 (±56.5) 33.4 1.36–247
fDON 91 (95.8%) 9.60 (±9.78) 6.47 ND–47.0
tDOM-1 32 (33.7%) 0.22 (±0.54) 0.05 ND–3.49
Age Age ≤ 12, n = 33
tDON 33 (100%) 63.2 (±52.6) 44.6 7.42–224
fDON 32 (97.0%) 11.3 (±10.5) 7.79 ND–47.0
tDOM-1 12 (36.4%) 0.16 (±0.25) 0.05 ND–1.05
12 < Age ≤ 18, n = 14
tDON 14 (100%) 73.1 (±61.0) 52.4 11.4–240
fDON 14 (100%) 13.0 (±10.8) 9.85 1.00–37.4
tDOM-1 5 (35.7%) 0.11 (±0.10) 0.05 ND–0.35
18 < Age ≤ 65, n = 68
tDON 68 (100%) 45.1 (±44.5) 29.8 3.31–213
fDON 65 (95.6%) 8.05 (±7.38) 5.79 ND–31.1
tDOM-1 21 (30.9%) 0.36 (±1.03) 0.05 ND–6.43
Age > 65, n = 36
tDON 36 (100%) 27.8 (±42.2) 10.98 1.36–247
fDON 29 (80.6%) 3.96 (±6.49) 2.48 ND–37.0
tDOM-1 8 (22.2%) 0.40 (±0.74) 0.05 ND–2.91

ND, level below LOD; positive samples refer to the levels higher than LOD.

When calculating the mean and median values, level below LOQ was set to half of the LOQ, and level below LOD was set to half of the LOD.