Table 1.
Characteristics of each component prevention intervention
| Intervention | Coverage assumption | Efficacy assumption | Unit cost value used in the analysisa |
|---|---|---|---|
| Male circumcision | Scaled up at a fixed rate: intervention unable to exceed 80% of eligible men, based on VMMC targets set 18. | Risk of infection for circumcised man 60% less than for other men 19, 20. | $60 per circumcision 21 |
| Behaviour change communication | The intervention is designed to reach 100% of the population‐with the adjustment in the partner change rate applied to the mean partner change rate in the entirety of the risk group. | 20% reduction in risk for each low‐risk person reached, 50% reduction in risk for high risk groups (MSM and FSW). | $20 annually in FSW and MSM, $10 annually in the low risk population 21 |
| Accelerated access to ART (Antiretroviral Therapy) i.e. active outreach for those with CD4 cell count > 350 cells per microlitre | Achievable coverage assumed to be 33% in low risk women and heterosexual men, 66% in FSW and MSM. | 85% reduction in risk of transmission for a person on ART relative to others 22. | $515 annually 23, 24, 25 |
| Pre‐exposure prophylaxis | The maximum PrEP coverage is assumed to be 25% in low risk women and heterosexual men and 50% in FSW and MSM. | 75% reduction in risk of infection for a person on PrEP relative to others 24. | $250 annually 24 |
a
Total costs of the programme are calculated using accounting identities.