. Author manuscript; available in PMC: 2018 Mar 2.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2016 Jan 29;171B(3):333–341. doi: 10.1002/ajmg.b.32408

TABLE I.

Filtering Cascade of Variants in Each of the Five MDD Families

Filter	Family I	Family II	Family III	Family IV	Family V
Total number of unique variants	119,967	147,031	120,158	124,920	121,048
Exonic nonsynonymous variants	11,485	15,042	11,492	13,121	11,476
Deleterious variants	3,915	5,142	3,860	4,448	3,940
Novel variants	382	438	319	464	333
Shared heterozygous variants	18	2	18	14	15