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. Author manuscript; available in PMC: 2018 Mar 2.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2016 Jan 29;171B(3):333–341. doi: 10.1002/ajmg.b.32408

TABLE I.

Filtering Cascade of Variants in Each of the Five MDD Families

Filter Family I Family II Family III Family IV Family V
Total number of unique variants 119,967 147,031 120,158 124,920 121,048
Exonic nonsynonymous variants 11,485 15,042 11,492 13,121 11,476
Deleterious variants 3,915 5,142 3,860 4,448 3,940
Novel variants 382 438 319 464 333
Shared heterozygous variants 18 2 18 14 15