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. 2018 Mar 2;37:41. doi: 10.1186/s13046-018-0718-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Characteristic expression pattern of OGN in human colorectal cancers. a High immunohistochemical staining of OGN in the cytoplasm of cancer cells in TMA samples. The representative pictures of low expression of OGN were also shown (b). c Kaplan Meier curves for overall survival for High OGN expression versus Low expression group. d Disease-free survival for High OGN expression versus Low expression group. e The optimal cut-off values of serum OGN levels are shown in histograms of the entire cohort (12.65 ng/ml). f Disease-free survival for high serum OGN level versus low serum level group