Fig. 1.

Peripheral MDSCs and M2-like macrophages in newly diagnosed ITP patients (n = 33) before treatment and health control (n = 18). a Representative dot plots of CD11b⁺CD33⁺HLA-DR⁻ MDSCs in the PBMCs of HC and ITP patients. b Representative dot plots of CD68⁺CD163⁺ M2-like macrophages in the PBMCs of HC and ITP patients. c Peripheral MDSCs were significantly elevated in ITP patients, with no respect of their later treatment response to HD-DXM regimen. d Peripheral M2-like macrophages were not found elevated in ITP patients, with no respect of their later treatment response to HD-DXM regimen. ***p < 0.001, compared to HC in two-tailed Student’s non-paired t test. Bars represented SD