Table 3.

Traditional and modified myeloablative (MA) regimens

MAC	Drug	Dose(total)	Schedule(d)	Donor type
Traditional
Cy/TBI	Cy	120 mg/kg	− 6, − 5	Allo-HSCT
	f-TBI	12 ~ 14 Gy	− 3 ~ − 1
Bu/Cy	Bu	16 mg/kg(po)or 12.8/kg(iv)	−7 ~ − 4	Allo-HSCT
	Cy	120 mg/kg	− 3, − 2
Modified (PUPH)
mBuCy	Hu	80 mg/kg, divided in twice	− 10	HLA-matched sibling HSCT
	Ara-C	2 g/m2	− 9
	Bu	9.6 mg/kg(iv)	− 8 ~ − 6
	Cy	3.6 g/m2	− 5, − 4
	MeCCNU	250 mg/m2(po)	− 3
mCy/TBI	Single TBI	770 cGy	− 6	HLA-matched sibling HSCT
	Cy	3.6 g/m2	− 5, -4
	MeCCNU	250 mg/m2	− 3
mBuCy+ATG	Ara-C	4~ 8 g/m2	− 10, − 9	URD, CBT, HID-HSCT
	Bu	9.6 mg/kg(iv)	− 8 ~ − 6
	Cy	3.6 g/m2	− 5, − 4
	ATG	10 mg/kg	−5 ~ − 2
	Or ATG-F	40 mg/kg	−5 ~ − 2
mCy/TBI + ATG	TBI	770 cGy	− 6	URD-HSCT, HID-HSCT
	Cy	3.6 g/m2	− 5, − 4
	MeCCNU	250 mg/m2	−3
	ATG	10 mg/kg	−5 ~ − 2
	Or ATG-F	40 mg/kg	−5 ~ − 2

Cy cyclophosphamide, Bu busulfan, TBI total body irradiation, Hu hydroxyurea, Ara-C cytarabine, MeCCNU methyl CCNU, ATG anti-thymocyte globulin thymoglobuline, ATG-F rabbit anti-thymocyte globulin produced by Fresenius, allo-HSCT allogeneic hematological stem cell transplantation, URD unrelated donor, CBT cord blood transplantation, HID-HSCT haploidentical transplantation. PUPH Peking University People Hospital