Skip to main content
. 2018 Feb 27;17:1533034618754475. doi: 10.1177/1533034618754475

Figure 5.

Figure 5.

Effects on gene expression following transfection of pancreatic cancer cell lines AsPC-1 and PANC-1 with ARID1A siRNA. Compared to the untreated group and negative control group, Bcl-2, CyclinD1, and KRAS mRNA levels of the ARID1A siRNA group were elevated. ARID1A, E-cadherin, and SMAD-3 mRNA levels were reduced. ARID1A indicates AT-rich interactive domain 1A; siRNA, small-interfering RNA. KRAS, kirsten rat sarcoma viral oncogene; Bcl-2, B-cell lymphoma-2.