Figure 2.

Summary of the results. Pain threshold, pain intensity ratings in response to fixed intensity stimuli and pain referral area, all determined during rectal distension, are different parameters to measure and quantify visceral pain sensitivity in irritable bowel syndrome. Somatization was associated with all measurements of pain sensitivity. Factors with independent effect on pain sensitivity are visualized with arrows toward “Pain sensitivity.” Factors with effect on pain sensitivity mediated by somatization are indicated with arrows toward “Somatization.” Cohort 1 is denoted C1, and Cohort 2, C2. This figure summarizes the findings from different analyses with the different visceral sensitivity measurements as the dependent variables, and not from one single comprehensive model.