Table 1.
Overview of the different questionnaires and visceral sensitivity measures used in both cohorts.
| Measurement | Cohort 1 (n = 231) | Cohort 2 (n = 141) |
|---|---|---|
| Questionnaires (independent variables) | ||
| Abuse history | x (n = 124) | x |
| Visceral Sensitivity Index (VSI) | x | x |
| Hospital Anxiety and Depression Scale (HADS) | x | x |
| Somatization | ||
| Patient Health Questionnaire (PHQ-15) | x (n = 107) | x |
| Symptom Checklist-90 (SCL-90) | x (n = 124) | |
| Visceral sensitivity measures (dependent variables)a | ||
| Pain thresholdb | x | x |
| Pain referral area | x | |
| Pain intensity rating at 36 mmHg rectal distension | x | |
a
All measures were obtained from rectal barostat investigations.
b
Different ascending method of limits barostat protocols were used in both cohorts (see supplementary materials for details).