Table 4.

Results of general linear model analyses—Cohort 2.

Dependent variable	Independent variable	Step 1 demographics and abuse		Step 2 + anxiety and depression		Step 3 + somatization
		β ± SE	p value	β ± SE	p value	β ± SE	p value
Pain threshold	Age	0.21 ± 0.06	0.0006	0.20 ± 0.06	0.002	0.20 ± 0.06	0.002
	Genderb	−4.5 ± 1.7	0.008	−4.4 ± 1.7	0.01	−4.1 ± 1.8	0.023
	Sexual abuse adultc	−4.0 ± 1.6	0.016	−4.0 ± 1.6	0.014	−3.9 ± 1.6	0.018
	GI-specific anxiety (VSI)			−0.09 ± 0.04	0.043	−0.08 ± 0.05	0.086
	Somatization (PHQ-15)					−0.08 ± 0.17	0.65
VAS pain intensity 36 mmHg rectal distensiona	Age	−0.01 ± 0.32	0.98	−0.07 ± 0.32	0.84	−0.05 ± 0.32	0.87
	Genderb	21.1 ± 8.5	0.014	21.9 ± 8.3	0.009	13.1 ± 9.1	0.15
	Sexual abuse adultc	8.6 ± 8.4	0.31	6.0 ± 8.3	0.48	5.8 ± 8.2	0.48
	Depression (HADS)			2.4 ± 1.2	0.042	1.6 ± 1.2	0.19
	GI-specific anxiety (VSI)			0.19 ± 0.25	0.46	0.07 ± 0.25	0.79
	Somatization (PHQ-15)					2.0 ± 0.9	0.032

Significant associations are shown in italics; effects which are mediated by somatization are underlined.

^aGeneral linear model analysis on ranked dependent variable.

^bReference category = men.

^cReference category = no abuse.

HADS: Hospital Anxiety and Depression Scale; GI: gastrointestinal; VSI: Visceral Sensitivity Index; PHQ: Patient Health Questionnaire; VAS: visual analog scale.