FIG. 4.

Representative gross morphology and histology of neocartilage engineered to examine the effects of compressive magnitude. Untreated control neocartilage displayed wavy or curved morphology, similar to that seen in Experiment 1, whereas all neocartilage constructs treated with passive axial compressive stimulation were flat. H&E staining showed highly cellular, homogeneous tissue, and no differences were found among groups. Neocartilage stained strongly for GAG and weakly for collagen. The scale bars represent 0.5 mm.