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. 2018 Mar 1;14(3):e1006846. doi: 10.1371/journal.ppat.1006846

Fig 4. Genome amplification and capsid protein expression in HPV16-infected HFK subjected to organotypic raft culture.

Fig 4

(A) Transcription profile of viral transcripts from rafts derived from HPV16-immortalized and -infected HFK. The data shown are fold changes normalized to E6 transcript levels. Error bars represent SEM of three independent experiments. (B) HPV16 genome is enriched in organotypic rafts over pEGFPN1 plasmid. (C) Thin cuts of organotypic rafts generated from HPV16-immortalized and -infected HFK cells subjected to HPV16-specific FISH. (D and E) E1^E4 (D) and L1 (E) protein are expressed in rafts grown from HPV16-infected HFK. Nuclei were stained with Dapi.