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. 2018 Feb 12;9(2):212. doi: 10.1038/s41419-017-0217-y

Fig. 2. Activation of GLP-1R by liraglutide decreases apoptosis in chondrocytes.

Fig. 2

a CCK-8 assays of chondrocytes treated with various concentrations of liraglutide for 24 h as shown above. b CCK-8 assays of liragltide-pretreated chondrocytes stimulated by IL-1β. c Chondrocytes were pretreated with liraglutide and then IL-1β and imaged by phase-contrast microscopy (20×). dg Representative western blots and quantification data of Bax, Bcl-2 and cleaved-caspase 3 in each group. Columns represent mean ± SD, Significant differences between the treatment and control groups are indicated as *P < 0.05, **P < 0.01, ***P < 0.001, n = 5