Fig. 3. The anti-apoptotic effects of GLP-1R was modulated by PI3K/Akt signaling in chondrocytes.

a, b Representative western blots and quantification data of p-Akt and Akt in each group. c, d TUNEL assay was used to assess the apoptosis of each group (scale bar: 50 μm). e, f Representative western blots and quantification data of p-Akt, Akt, Bax, Bcl-2, and cleaved-caspase 3 in each group. Columns represent mean ± SD, Significant differences between the treatment and control groups are indicated as *P < 0.05, **P < 0.01, ***P < 0.001, n = 5