Fig. 8. miR-143-3p downregulates PLGF expression through the ITGA6/PI3K/AKT /STAT3 pathways.

a Western blot analysis of relevant proteins in the MAPK/ERK and PI3K/AKT pathways in GBC cells that were transfected with mimic (inhibitor) NC or miR-143-3p mimics (inhibitors). b Western blot analysis of relevant proteins in the MAPK/ERK and PI3K/AKT pathways in GBC cells that were co-transfected with mimic NC or miR-143-3p mimic and empty vector or ITGA6. c Working model of the miR-143-3p regulatory axis in GBC