Fig. 2. P53 or NGF was candidate gene of miR-675 or let-7a, respectively (*P < 0.05 compared with the control).
a miR-675 evidently inhibited luciferase activity of wild-type P53 3′UTR but not that of mutant P53 3′UTR in U87 cells. b miR-675 evidently inhibited luciferase activity of wild-type P53 3′UTR but not that of mutant P53 3′UTR in U251 cells. c Luciferase activity of wild-type but not mutant NGF 3′UTR in U87 cells transfected with let-7a mimic was much lower. d Luciferase activity of wild-type but not mutant NGF 3′UTR in U251 cells transfected with let-7a mimic was much lower