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. 2018 Feb 14;9(2):221. doi: 10.1038/s41419-018-0315-5

Fig. 6. Progression of PAH was partially inhibited in SM22α-GZMB Tg mice.

Fig. 6

a SM22α-GZMB Tg mice showed reversal of the wall thickening a, b, depressed pulmonary vascular density c, mean RVSP d, and indices of RV weight (RV/LV+Sep) e, induced by chronic hypoxia. All panels are at × 20 magnification. Scale bars = 50 μm; n = 10. Data are represented as mean ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001 versus wild type group. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus hypoxia + wild-type group. HYP, hypoxia; WT, wild type