Fig. 4. Oral NEN treatment reduces intestinal polyps in APC^min/+ mice.

a, b Representative pictures of intestine fragments from control or NEN fed mice, respectively. Arrows point to areas containing polyps. Scale bars, 5 mm. c Quantification of intestinal polyps in control or NEN fed mice (n = 10 in each group). Mice at age of 2 months fed either normal chow diet or diet containing 1500 ppm NEN for 8 weeks. Polyps in intestine of each mouse were counted. Results shown as means ± SD. Statistical significance (P) was determined by student-t test between the control and NEN fed mice: ***P < 0.001. The data are representative results from two independent experiments