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. 2017 Nov 20;178(1):55–63. doi: 10.1001/jamainternmed.2017.3919

Table 3. Results From Secondary Analyses That Expanded the Population by Including Patients Who Had Used Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers in the Past 180 Days.

Variable Ramipril
(n = 8656)
Telmisartan
(n = 8656)
Composite End Point
No. of person-years 10 227 8749
No. of events 799 695
Incidence rate per 1000 person-years 78.13 79.44
Unadjusted 1 [Reference] 0.96 (0.89-1.04)
PS matched 1 [Reference] 0.97 (0.88-1.08)
Stroke
No. of person-years 10 760 9098
No. of events 184 173
Incidence rate per 1000 person-years 17.1 19.01
Unadjusted 1 [Reference] 1.08 (0.92-1.27)
PS matched 1 [Reference] 1.07 (0.87-1.32)
Myocardial Infarction
No. of person-years 10 755 9132
No. of events 156 126
Incidence rate per 1000 person-years 14.5 13.8
Unadjusted 1 [Reference] 0.87 (0.72-1.04)
PS matched 1 [Reference] 0.91 (0.72-1.15)
Hospitalization for Heart Failure
No. of person-years 10 433 8928
No. of events 589 481
Incidence rate per 1000 person-years 56.46 53.88
Unadjusted 1 [Reference] 0.93 (0.84-1.02)
PS matched 1 [Reference] 0.91 (0.81-1.03)
Angioedema
No. of person-years 10 885 9220
No. of events 32 10
Incidence rate per 1000 person-years 2.94 1.08
Unadjusted 1 [Reference] 0.43 (0.23-0.82)
PS matched 1 [Reference] 0.35 (0.17-0.71)

Abbreviation: PS, propensity score.