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. 2018 Jan 26;9(2):128. doi: 10.1038/s41419-017-0141-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Schematic of the experimental design used to analyze the proliferation, DNA repair capacity and apoptosis in SAA-iPSC-derived-hematopoietic progenitors; b Analysis of BrdU-incorporating cells in WT and SAA iPSC-derived-hematopoietic progenitors. One-way ANOVA with Dunnett’s multiple comparison test was used for statistical comparison between WT and SAA cell lines; c Analysis of γH2AX in BrdU+ cells in untreated (dark blue bars), 1 h after HU recovery (beige bars) and 24 h after HU recovery (red bars) iPSC-derived-hematopoietic progenitors. One-way ANOVA with Tukey’s multiple comparison test was used for statistical comparison between untreated cells and 1 h after HU recovery and 24 h after recovery; d Analysis of γH2AX in BrdU+ cells in WT and SAA iPSC-derived-hematopoietic progenitors. One-way ANOVA with Dunnett’s multiple comparison test was used for statistical comparison between WT and SAA cell lines; e Analysis of γH2AX in BrdU- cells in untreated (dark blue bars), 1 h after HU recovery (beige bars) and 24 h after HU recovery (red bars) iPSC-derived-hematopoietic progenitors. One-way ANOVA with Tukey’s multiple comparison test was used for statistical comparison between untreated cells and 1 h after HU recovery and 24 h after recovery,(*p < 0.05); f Analysis of γH2AX in BrdU- cells in WT and SAA iPSC-derived-hematopoietic progenitors. One-way ANOVA with Dunnett’s multiple comparison test was used for statistical comparison between WT and SAA cell lines. b–f data is presented as mean of at least 3 independent experiments ± S.E.M. Data for all control cell lines is averaged in one group (WT)