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. 2018 Feb 15;9(3):271. doi: 10.1038/s41419-018-0320-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a The correlation between KRas and PEAK1 expression was evaluated by Spearman’s method. b qRT-PCR analysis of the expression of KRas and PEAK1 in CRC cells infected with pLenti-KRas or pLenti-vector. c Western blot analyses of the expression of KRas, PEAK1 and Erk extracts from CRC cells infected with pLenti-KRas or pLenti-vector. d qRT-PCR analysis of the expression of KRas and PEAK1 in CRC cells transfected with siKRas or NC. e Western blot analyses of the expression of KRas, PEAK1 and Erk in CRC cells transfected with siKRas or NC. These experiments were repeated three times. (Data are represented as the mean ± s.d. *P < 0.05, **P < 0.01, ***P < 0.001)