Table 2. Comparison of Long-term Outcomes by Groupa.
| Outcome Measure | All (N = 64) |
TORS Only (n = 15) |
TORS + RT (n = 29) |
TORS + CRT (n = 20) |
Effect Size, η2b | Post Hoc Comparisons, Mean Difference (95% CI) | ||
|---|---|---|---|---|---|---|---|---|
| TORS Only vs TORS + RT | TORS Only vs TORS + CRT | TORS + RT vs TORS + CRT | ||||||
| Time postoperatively, mo | 21 (12 to 36) | 22.50 (12 to 36) | 20 (13 to 36) | 22 (14 to 33) | .004 | 1.16 (−4.76 to 7.09) | −0.01 (−6.35 to 6.34) | −1.16 (−6.46 to 4.13) |
| Weight loss, mean (SD), lbc | 19.70 (17.03) | 7.92 (9.24) | 24.02 (16.69) | 22.50 (18.51) | .153d | −16.10 (−29.79 to −2.41)e | −14.58 (−29.19 to .03) | 1.52 (−11.01 to 14.04) |
| PSS–Normalcy of Diet | 100 (10 to 100) | 100 (60 to 100) | 100 (50 to 100) | 90 (10 to 100) | .102 | 7.72 (−10.00 to 25.45) | 18.00 (−1.30 to 37.03) | 10.28 (−5.92 to 26.47) |
| PSS–Eating in Public | 87.50 (0 to 100) | 100 (75 to 100) | 75 (50 to 100) | 75 (0 to 100) | .143f | 9.66 (−6.58 to 25.89) | 21.75 (4.32 to 39.18)d | 12.09 (−2.74 to 26.93) |
| PSS–Speech Understandability | 100 (25 to 100) | 100 (75 to 100) | 100 (50 to 100) | 100 (25 to 100) | .009 | 0.29 (−13.12 to 13.70) | −0.83 (−15.24 to 13.57) | −1.12 (−13.38 to 11.13) |
| EAT-10 | 7 (0 to 36) | 4.50 (0 to 22) | 9.50 (0 to 36) | 9.50 (0 to 32) | .080 | −5.72 (−14.34 to 2.89) | −8.05 (−17.30 to 1.20) | −2.33 (−10.20 to 5.55) |
| HNQOL-Eating | 83.33 (25 to 100) | 89.59 (66.67 to 100) | 83.33 (25 to 100) | 68.34 (33.33 to 95.83) | .165f | 13.18 (−2.76 to 29.12) | 21.15 (4.04 to 38.27)e | 7.97 (−6.59 to 22.53) |
| HNQOL-Speech | 93.75 (0 to 100) | 100 (0 to 100) | 93.75 (25 to 100) | 84.38 (37.50 to 100) | .017 | −1.04 (−20.11 to 18.67) | 0.72 (−21.86 to 19.78) | 1.04 (−18.04 to 17.40) |
| HNQOL-Emotion | 91.67 (33.33 to 100) | 93.75 (66.67 to 100) | 91.67 (37.50 to 100) | 87.50 (33.33 to 100) | .011 | 6.12 (−8.73 to 20.97) | 6.81 (−9.14 to 22.76) | 0.69 (−12.88 to 14.26) |
| HNQOL-Pain | 87.50 (25 to 100) | 90.63 (62.50 to 100) | 90.63 (25 to 100) | 84.38 (37.50 to 100) | .023 | 3.69 (−12.16 to 19.55) | 8.54 (−8.48 to 25.57) | 4.85 (−9.64 to 19.34) |
Abbreviations: CRT, chemoradiotherapy; EAT-10, 10-Item Eating Assessment Tool; HNQOL, Head and Neck Quality of Life; PSS, Performance Status Scale; RT, radiotherapy; TORS, transoral robotic surgery.
a
Data are presented as mean score (95% CI) unless otherwise indicated.
b
F tests for determining effect sizes for means.
c
To convert to kilograms, multiply by 0.45.
d
Significant difference using analysis of variance with α adjustment for multiple comparisons.
e
Significant between-group difference.
f
Significant difference using Kruskal-Wallis test with α adjustment for multiple comparisons.