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. 2017 Nov 29;153(1):e174591. doi: 10.1001/jamasurg.2017.4591

Table 2. Multivariate Analysis of Factors Predictive of Locoregional Recurrence–Free Survival, Disease-Free Survival, Distant Metastasis–Free Survival, and Overall Survival.

Variable Hazard Ratio (95% CI) P Value
Locoregional Recurrence–Free Survival
Treatment with chemotherapy + RT 0.08 (0.02-0.39) <.01
Age 0.93 (0.88-0.98) .01
Tumor size 1.01 (0.72-1.42) .95
No. of lymph nodes removed 0.93 (0.84-1.02) .13
Pathologic T stage
pT2 1.19 (0.12-12.01) .88
pT4 1.59 (0.40-6.38) .51
Disease-Free Survival
Treatment with chemotherapy + RT 0.53 (0.27-1.06) .07
Age 0.97 (0.93-0.99) .04
Tumor size 1.03 (0.83-1.27) .80
Pathologic T stage
pT2 0.24 (0.03-1.78) .16
pT4 1.30 (0.58-2.94) .52
Distant Metastasis–Free Survival
Treatment with chemotherapy + RT 1.01 (0.37-2.76) .99
Age 0.96 (0.92-1.01) .12
Tumor size 0.93 (0.69-1.25) .63
No. of lymph nodes removed 1.08 (1.00-1.16) .05
Pathologic T stage
pT2 1 [Reference] NA
pT4 1.47 (0.48-4.54) .50
Overall Survival
Treatment with chemotherapy + RT 0.61 (0.33-1.11) .11
Age 0.98 (0.95-1.01) .27
Tumor size 0.98 (0.81-1.18) .83
Pathologic T stage
pT2 0.18 (0.02-1.34) .10
pT4 1.29 (0.63-2.64) .49

Abbreviations: NA, not applicable; RT, radiotherapy.